Phospho chk2 antibody
WebThe oncogenic cytoplasmic p21 contributes to cancer aggressiveness and chemotherapeutic failure. However, the molecular mechanisms remain obscure. Here, we show for the first time that cytoplasmic p21 mediates 5-Fluorouracil (5FU) resistance by shuttling p-Chk2 out of the nucleus to protect the tumor cells from its pro-apoptotic … WebCHK2 (also known as CHEK2, Protein kinase CHK2 isoform a, and checkpoint-like protein) is a serine/ threonine-protein kinase involved in the control of cell cycle checkpoints and …
Phospho chk2 antibody
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WebFlow Cytometry - FITC Anti-Chk2 (phospho T68) antibody [Chk2T68-D12] (ab278651) Flow cytometric analysis of Hela cells treated with lambda phosphatase (red) or treated with … WebMar 21, 2024 · CHEK2 (Checkpoint Kinase 2) is a Protein Coding gene. Diseases associated with CHEK2 include Prostate Cancer and Li-Fraumeni Syndrome 2 . Among its related pathways are Regulation of activated PAK …
WebJun 30, 2024 · Membranes were incubated in 5% nonfat milk for 45 min at room temperature and then incubated for 18 hours at 4°C with primary antibodies against the following molecules diluted in 5% nonfat milk: p21, p27, phospho-Chk1, Chk1, phospho-Chk2, Chk2, ZEB1, ZEB2, p53, and γH2AX (table S10). WebPhospho-Chk2 (Ser19) Antibody detects endogenous levels of Chk2 only when phosphorylated at serine 19. The antibody does not cross-react with Chk2 phosphorylated at other sites. Species Reactivity: Human Source / Purification
WebPolyclonal antibodies are produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Thr68 of human Chk2. Antibodies are purified by protein A and peptide affinity chromatography. Validations None provided Applications Immunoprecipitation (IP) Reactivity Chlorocebus sabaeus (Green monkey) WebInvitrogen Anti-Phospho-CHK2 (Thr68) Polyclonal, Catalog # PA5-17818. Tested in Western Blot (WB), Immunocytochemistry (ICC/IF), Flow Cytometry (Flow) and …
WebPhospho-CHK2 (Ser19) Polyclonal Antibody Catalog Number PA5-17731 Product Data Sheet Product Specific Information ... surrounding pSer19 of human Chk2 Conjugate Unconjugated Form Liquid Purification Antigen affinity chromatography …
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