WebNov 1, 2024 · We explored the molecular characteristics of CBX4 in GC, and high CBX4 mutation rate (9%) was found. Enhanced CBX4 mRNA expression was the most common alteration. These results suggested that the expression of CBX4 is remarkably related to GC patient prognosis and that CBX4 might be developed as a useful biomarker to predict … WebChromobox 4 (CBX4), a member of the Polycomb group (PcG) family of epigenetic regulatory factors, enhances cellular proliferation and promotes cancer cell migration. However, the effect of CBX4 in the progression of lung cancer is not fully understood. We found that CBX4 is highly expressed in lung tumours compared with adjacent normal …
The SUMO E3 ligase CBX4 is identified as a poor prognostic marker of g…
WebELISA: CBX4 Antibody (6C5G3) [NBP2-52432] - Black line: Control Antigen (100 ng); Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng). Product Details Summary Order Details Loading... View Available Formulations 100% Guarantee on every product Datasheet Reviews & Publications Protocols & FAQs Support & Research WebUseful information about the protein provided by UniProt. E3 SUMO-protein ligase which facilitates SUMO1 conjugation by UBE2I 1. Involved in the sumoylation of HNRNPK, a … top substack authors
CBX4 Antibody Cell Signaling Technology
WebMar 1, 2024 · CBX1, CBX2, CBX3, CBX4, CBX5, CBX6, CBX7 and CBX8 levels were assessed based on 442, 367, 455, 421, 451, 392, 351 and 337 samples, respectively. These CBXs were dysregulated in multiple cancer types. CBX1 was upregulated in 21 datasets but downregulated in 3 datasets. CBX2 mRNA levels were enhanced in 23 Discussion WebMar 13, 2024 · Cbx4 Gene Is Marked by H3K27me3 in Brown Preadipocytes and Is Selectively Expressed in BAT. A significant subset of BAT-selective genes, including key thermogenic transcriptional regulators such as Prdm16, Pparα, and Pgc1β, was marked by H3K27me3 at their promoter/enhancer regions in brown preadipocytes (Pan et al., … WebThis second set of CBX proteins resides in PRC1, which has many subunits including other polycomb group factors (PCGF1, PCGF2, PCGF3, PCGF4, PCGF5, PCGF6), human polyhomeotic homologs (HPH1, HPH2, HPH3) and E3-ubiquitin ligases (RING1 or RING2). The latter enzymes catalyze the subsequent mono-ubiquitination of lysine 119 in H2A … top subtitles site